藥物交互作用
Amiodarone + Arsenic trioxide
嚴重程度: 禁忌併用
Amiodarone and Arsenic trioxide: contraindicated interaction.
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摘要
Arsenic trioxide markedly prolongs the QT interval and can cause torsades de pointes, and amiodarone adds to this risk. Labeling advises against combining it with other QT-prolonging drugs.
用白話說明這項交互作用的意義
Amiodarone and Arsenic trioxide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Amiodarone belongs to Cardiovascular; Arsenic trioxide belongs to Oncology.
為什麼會發生
Additive prolongation of cardiac repolarization.
處置方式
Avoid the combination and choose a non-QT-prolonging alternative to amiodarone. If it cannot be avoided, monitor ECG continuously or frequently and maintain potassium and magnesium.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Amiodarone 的其他交互作用
Arsenic trioxide 的其他交互作用
常見問題
Can I take Amiodarone with Arsenic trioxide?
MediHelp rates the interaction as contraindicated. Amiodarone and Arsenic trioxide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Arsenic trioxide markedly prolongs the QT interval and can cause torsades de pointes, and amiodarone adds to this risk. Labeling advises against combining it with other QT-prolonging drugs.
How serious is the interaction between Amiodarone and Arsenic trioxide?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose a non-QT-prolonging alternative to amiodarone. If it cannot be avoided, monitor ECG continuously or frequently and maintain potassium and magnesium.
What other medicines interact with Amiodarone?
MediHelp also lists interactions of Amiodarone with, for example, Amisulpride, Dofetilide, Dronedarone. The full list is on the Amiodarone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
