藥物交互作用
Atenolol + Atenolol-chlorthalidone
嚴重程度: 嚴重
Atenolol and Atenolol-chlorthalidone: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
The combination product already contains atenolol, so adding atenolol duplicates therapy. This leads to excess beta-blockade, with bradycardia, hypotension and fatigue.
用白話說明這項交互作用的意義
Atenolol and Atenolol-chlorthalidone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Atenolol belongs to Cardiovascular; Atenolol-chlorthalidone belongs to Cardiovascular.
為什麼會發生
Therapeutic duplication of beta-1 adrenergic blockade leading to additive pharmacodynamic effects.
處置方式
Avoid concurrent use; prescribe a single atenolol-containing product and adjust the dose by heart rate and blood pressure.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Atenolol-chlorthalidone 的其他交互作用
Atenolol 的其他交互作用
常見問題
Can I take Atenolol with Atenolol-chlorthalidone?
MediHelp rates the interaction as major. Atenolol and Atenolol-chlorthalidone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. The combination product already contains atenolol, so adding atenolol duplicates therapy. This leads to excess beta-blockade, with bradycardia, hypotension and fatigue.
How serious is the interaction between Atenolol and Atenolol-chlorthalidone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use; prescribe a single atenolol-containing product and adjust the dose by heart rate and blood pressure.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
