藥物交互作用
Atenolol + Carvedilol
嚴重程度: 嚴重
Atenolol and Carvedilol: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Carvedilol is a nonselective beta blocker with alpha-1 blocking activity, so adding atenolol duplicates beta blockade. This can cause excessive bradycardia, hypotension and AV block.
用白話說明這項交互作用的意義
Atenolol and Carvedilol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Atenolol belongs to Cardiovascular; Carvedilol belongs to Cardiovascular.
為什麼會發生
Additive pharmacodynamic beta-adrenergic blockade, with added alpha-1 blockade from carvedilol.
處置方式
Avoid combining them and use one beta blocker. If overlap occurs during a change, monitor heart rate and blood pressure.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Atenolol 的其他交互作用
Carvedilol 的其他交互作用
常見問題
Can I take Atenolol with Carvedilol?
MediHelp rates the interaction as major. Atenolol and Carvedilol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Carvedilol is a nonselective beta blocker with alpha-1 blocking activity, so adding atenolol duplicates beta blockade. This can cause excessive bradycardia, hypotension and AV block.
How serious is the interaction between Atenolol and Carvedilol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining them and use one beta blocker. If overlap occurs during a change, monitor heart rate and blood pressure.
What other medicines interact with Atenolol?
MediHelp also lists interactions of Atenolol with, for example, Amifostine, Amiodarone, Atenolol-chlorthalidone. The full list is on the Atenolol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
