藥物交互作用
Atracurium + Benzhydrocodone / acetaminophen
嚴重程度: 嚴重
Atracurium and Benzhydrocodone / acetaminophen: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Opioids combined with neuromuscular blockers can add to respiratory compromise, and the opioid's sedation may mask inadequate ventilation. Atracurium is used only with ventilatory support, so the practical risk arises when residual blockade overlaps with opioid-induced respiratory depression.
用白話說明這項交互作用的意義
Atracurium and Benzhydrocodone / acetaminophen can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive respiratory depression: central opioid-mediated depression plus peripheral neuromuscular blockade.
處置方式
Use only with controlled ventilation and monitor neuromuscular blockade and respiratory status until full recovery. Use the lowest effective opioid dose and duration.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Atracurium 的其他交互作用
常見問題
Can I take Atracurium with Benzhydrocodone / acetaminophen?
MediHelp rates the interaction as major. Atracurium and Benzhydrocodone / acetaminophen can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Opioids combined with neuromuscular blockers can add to respiratory compromise, and the opioid's sedation may mask inadequate ventilation. Atracurium is used only with ventilatory support, so the practical risk arises when residual blockade overlaps with opioid-induced respiratory depression.
How serious is the interaction between Atracurium and Benzhydrocodone / acetaminophen?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only with controlled ventilation and monitor neuromuscular blockade and respiratory status until full recovery. Use the lowest effective opioid dose and duration.
What other medicines interact with Atracurium?
MediHelp also lists interactions of Atracurium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Atracurium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
