藥物交互作用
Atropine iv / + Umeclidinium
嚴重程度: 中度
Atropine iv / and Umeclidinium: moderate interaction.
最後更新
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摘要
Systemic atropine adds antimuscarinic effects to inhaled umeclidinium. Tachycardia, dry mouth, urinary retention and constipation may be increased, though single clinical doses of atropine are usually tolerated.
用白話說明這項交互作用的意義
Atropine iv / and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Additive muscarinic receptor antagonism.
處置方式
Monitor heart rate and for urinary retention when atropine is given, especially with repeated doses. Avoid long-term combination of systemic antimuscarinics with umeclidinium where possible.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Umeclidinium 的其他交互作用
常見問題
Can I take Atropine iv / with Umeclidinium?
MediHelp rates the interaction as moderate. Atropine iv / and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic atropine adds antimuscarinic effects to inhaled umeclidinium. Tachycardia, dry mouth, urinary retention and constipation may be increased, though single clinical doses of atropine are usually tolerated.
How serious is the interaction between Atropine iv / and Umeclidinium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and for urinary retention when atropine is given, especially with repeated doses. Avoid long-term combination of systemic antimuscarinics with umeclidinium where possible.
What other medicines interact with Umeclidinium?
MediHelp also lists interactions of Umeclidinium with, for example, Tiotropium, Aclidinium, Atropine. The full list is on the Umeclidinium page.
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