藥物交互作用
Belladonna alkaloids + Umeclidinium
嚴重程度: 中度
Belladonna alkaloids and Umeclidinium: moderate interaction.
最後更新
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摘要
Belladonna alkaloids such as atropine, hyoscyamine and scopolamine are antimuscarinic and add to the effects of umeclidinium. This can cause dry mouth, constipation, urinary retention, tachycardia and confusion in older adults.
用白話說明這項交互作用的意義
Belladonna alkaloids and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Additive muscarinic receptor antagonism.
處置方式
Avoid concurrent use where an alternative exists. If needed, monitor for urinary retention, constipation and CNS effects, particularly in older patients.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Umeclidinium 的其他交互作用
常見問題
Can I take Belladonna alkaloids with Umeclidinium?
MediHelp rates the interaction as moderate. Belladonna alkaloids and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Belladonna alkaloids such as atropine, hyoscyamine and scopolamine are antimuscarinic and add to the effects of umeclidinium. This can cause dry mouth, constipation, urinary retention, tachycardia and confusion in older adults.
How serious is the interaction between Belladonna alkaloids and Umeclidinium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where an alternative exists. If needed, monitor for urinary retention, constipation and CNS effects, particularly in older patients.
What other medicines interact with Umeclidinium?
MediHelp also lists interactions of Umeclidinium with, for example, Tiotropium, Aclidinium, Atropine iv /. The full list is on the Umeclidinium page.
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