藥物交互作用
Avapritinib + Cetirizine
嚴重程度: 中度
Avapritinib and Cetirizine: moderate interaction.
最後更新
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摘要
Avapritinib can cause cognitive effects such as memory impairment, confusion and drowsiness, and cetirizine may add to sedation. The combination may worsen mental clouding.
用白話說明這項交互作用的意義
Avapritinib and Cetirizine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Avapritinib belongs to Oncology; Cetirizine belongs to Respiratory.
為什麼會發生
Additive CNS depressant effects; avapritinib has its own neurocognitive toxicity.
處置方式
Monitor cognition and alertness, and use a nonsedating alternative or lower cetirizine dose if cognitive symptoms appear. Follow avapritinib dose-modification guidance for cognitive adverse effects.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cetirizine 的其他交互作用
Avapritinib 的其他交互作用
常見問題
Can I take Avapritinib with Cetirizine?
MediHelp rates the interaction as moderate. Avapritinib and Cetirizine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Avapritinib can cause cognitive effects such as memory impairment, confusion and drowsiness, and cetirizine may add to sedation. The combination may worsen mental clouding.
How serious is the interaction between Avapritinib and Cetirizine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor cognition and alertness, and use a nonsedating alternative or lower cetirizine dose if cognitive symptoms appear. Follow avapritinib dose-modification guidance for cognitive adverse effects.
What other medicines interact with Cetirizine?
MediHelp also lists interactions of Cetirizine with, for example, Acrivastine, Amisulpride, Asenapine. The full list is on the Cetirizine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。