藥物交互作用
Avelumab + Cefadroxil
嚴重程度: 中度
Avelumab and Cefadroxil: moderate interaction.
最後更新
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摘要
Antibiotics may alter gut microbiota, and observational data in cancer patients suggest antibiotic exposure around the start of checkpoint inhibitor therapy is associated with poorer outcomes. A causal effect of cefadroxil has not been established.
用白話說明這項交互作用的意義
Avelumab and Cefadroxil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Avelumab belongs to Oncology; Cefadroxil belongs to Anti Bacterial.
為什麼會發生
Antibiotic-induced gut dysbiosis may impair immune responses that support checkpoint inhibitor efficacy; the mechanism is not firmly established.
處置方式
Use antibiotics only when clearly indicated and for the shortest effective duration. Monitor tumor response as usual.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Cefadroxil 的其他交互作用
Avelumab 的其他交互作用
常見問題
Can I take Avelumab with Cefadroxil?
MediHelp rates the interaction as moderate. Avelumab and Cefadroxil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Antibiotics may alter gut microbiota, and observational data in cancer patients suggest antibiotic exposure around the start of checkpoint inhibitor therapy is associated with poorer outcomes. A causal effect of cefadroxil has not been established.
How serious is the interaction between Avelumab and Cefadroxil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use antibiotics only when clearly indicated and for the shortest effective duration. Monitor tumor response as usual.
What other medicines interact with Cefadroxil?
MediHelp also lists interactions of Cefadroxil with, for example, Amikacin, Balstilimab, Bcg vaccine live. The full list is on the Cefadroxil page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
