藥物交互作用
Bcg vaccine live + Cabazitaxel
嚴重程度: 嚴重
Bcg vaccine live and Cabazitaxel: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Cabazitaxel is immunosuppressive, and a live attenuated BCG vaccine can cause disseminated BCG infection in immunocompromised patients. The immune response to the vaccine may also be inadequate.
用白話說明這項交互作用的意義
Bcg vaccine live and Cabazitaxel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Chemotherapy-induced immunosuppression impairs control of live attenuated bacteria and reduces vaccine response.
處置方式
Avoid live BCG vaccination during cabazitaxel therapy and for at least 3 months afterward.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Cabazitaxel 的其他交互作用
常見問題
Can I take Bcg vaccine live with Cabazitaxel?
MediHelp rates the interaction as major. Bcg vaccine live and Cabazitaxel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cabazitaxel is immunosuppressive, and a live attenuated BCG vaccine can cause disseminated BCG infection in immunocompromised patients. The immune response to the vaccine may also be inadequate.
How serious is the interaction between Bcg vaccine live and Cabazitaxel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live BCG vaccination during cabazitaxel therapy and for at least 3 months afterward.
What other medicines interact with Cabazitaxel?
MediHelp also lists interactions of Cabazitaxel with, for example, Adenovirus types 4 and 7 live, Atazanavir, Bcg intravesical live. The full list is on the Cabazitaxel page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
