藥物交互作用
Belladonna and opium + Clonazepam
嚴重程度: 嚴重
Belladonna and opium and Clonazepam: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
The opium component is an opioid, and combining it with a benzodiazepine raises the risk of profound sedation, respiratory depression, coma and death. Belladonna anticholinergic effects may add to confusion in older patients.
用白話說明這項交互作用的意義
Belladonna and opium and Clonazepam can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive CNS and respiratory depression between opioid and benzodiazepine.
處置方式
Avoid combination where possible; otherwise use the lowest doses for the shortest time. Monitor respiratory status and sedation, and counsel on warning signs.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Clonazepam 的其他交互作用
常見問題
Can I take Belladonna and opium with Clonazepam?
MediHelp rates the interaction as major. Belladonna and opium and Clonazepam can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. The opium component is an opioid, and combining it with a benzodiazepine raises the risk of profound sedation, respiratory depression, coma and death. Belladonna anticholinergic effects may add to confusion in older patients.
How serious is the interaction between Belladonna and opium and Clonazepam?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combination where possible; otherwise use the lowest doses for the shortest time. Monitor respiratory status and sedation, and counsel on warning signs.
What other medicines interact with Clonazepam?
MediHelp also lists interactions of Clonazepam with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Alfentanil. The full list is on the Clonazepam page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
