藥物交互作用
Bendroflumethiazide + Hydrochlorothiazide-lisinopril
嚴重程度: 嚴重
Bendroflumethiazide and Hydrochlorothiazide-lisinopril: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Combining two thiazide diuretics duplicates therapy and increases the risk of hypokalemia, hyponatremia, hypotension and renal impairment without clear added benefit.
用白話說明這項交互作用的意義
Bendroflumethiazide and Hydrochlorothiazide-lisinopril can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Duplicate inhibition of the distal tubule sodium-chloride cotransporter with additive electrolyte loss and volume depletion.
處置方式
Avoid using two thiazides together and stop one of them. Monitor electrolytes and renal function if overlap occurs.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Hydrochlorothiazide-lisinopril 的其他交互作用
常見問題
Can I take Bendroflumethiazide with Hydrochlorothiazide-lisinopril?
MediHelp rates the interaction as major. Bendroflumethiazide and Hydrochlorothiazide-lisinopril can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Combining two thiazide diuretics duplicates therapy and increases the risk of hypokalemia, hyponatremia, hypotension and renal impairment without clear added benefit.
How serious is the interaction between Bendroflumethiazide and Hydrochlorothiazide-lisinopril?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two thiazides together and stop one of them. Monitor electrolytes and renal function if overlap occurs.
What other medicines interact with Hydrochlorothiazide-lisinopril?
MediHelp also lists interactions of Hydrochlorothiazide-lisinopril with, for example, Dofetilide, Sacubitril / valsartan, Amifostine. The full list is on the Hydrochlorothiazide-lisinopril page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
