藥物交互作用
Benzhydrocodone / acetaminophen + Chloral hydrate
嚴重程度: 嚴重
Benzhydrocodone / acetaminophen and Chloral hydrate: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Chloral hydrate combined with an opioid can cause profound sedation, respiratory depression, coma and death. The risk rises with higher doses and longer durations.
用白話說明這項交互作用的意義
Benzhydrocodone / acetaminophen and Chloral hydrate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive CNS and respiratory depression from sedative-hypnotic and opioid effects.
處置方式
Reserve combined use for patients with no adequate alternatives, using the lowest doses and shortest duration. Monitor closely for sedation and respiratory depression.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Chloral hydrate 的其他交互作用
常見問題
Can I take Benzhydrocodone / acetaminophen with Chloral hydrate?
MediHelp rates the interaction as major. Benzhydrocodone / acetaminophen and Chloral hydrate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Chloral hydrate combined with an opioid can cause profound sedation, respiratory depression, coma and death. The risk rises with higher doses and longer durations.
How serious is the interaction between Benzhydrocodone / acetaminophen and Chloral hydrate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Reserve combined use for patients with no adequate alternatives, using the lowest doses and shortest duration. Monitor closely for sedation and respiratory depression.
What other medicines interact with Chloral hydrate?
MediHelp also lists interactions of Chloral hydrate with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Alfentanil. The full list is on the Chloral hydrate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
