藥物交互作用
Benzhydrocodone / acetaminophen + Eszopiclone
嚴重程度: 嚴重
Benzhydrocodone / acetaminophen and Eszopiclone: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Opioids combined with sedative-hypnotics such as eszopiclone carry a risk of profound sedation, respiratory depression, coma and death. This is a labeled warning for opioid products.
用白話說明這項交互作用的意義
Benzhydrocodone / acetaminophen and Eszopiclone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive CNS and respiratory depression from opioid receptor agonism and GABA-A modulation.
處置方式
Reserve the combination for patients with no adequate alternatives, with the lowest effective doses and shortest duration. Monitor for sedation and respiratory depression.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Eszopiclone 的其他交互作用
常見問題
Can I take Benzhydrocodone / acetaminophen with Eszopiclone?
MediHelp rates the interaction as major. Benzhydrocodone / acetaminophen and Eszopiclone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Opioids combined with sedative-hypnotics such as eszopiclone carry a risk of profound sedation, respiratory depression, coma and death. This is a labeled warning for opioid products.
How serious is the interaction between Benzhydrocodone / acetaminophen and Eszopiclone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Reserve the combination for patients with no adequate alternatives, with the lowest effective doses and shortest duration. Monitor for sedation and respiratory depression.
What other medicines interact with Eszopiclone?
MediHelp also lists interactions of Eszopiclone with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Amobarbital. The full list is on the Eszopiclone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
