藥物交互作用
Betamethasone + Levofloxacin
嚴重程度: 嚴重
Betamethasone and Levofloxacin: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Using a fluoroquinolone together with a systemic corticosteroid increases the risk of tendinitis and tendon rupture, particularly of the Achilles tendon. The risk is higher in older adults and transplant patients.
用白話說明這項交互作用的意義
Betamethasone and Levofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Betamethasone belongs to Endocrine; Levofloxacin belongs to Anti Bacterial.
為什麼會發生
Both drugs have adverse effects on tendon tissue and collagen integrity, and the effects appear to be additive.
處置方式
Avoid the combination where possible, especially in patients over 60. Stop levofloxacin and rest the limb if tendon pain or swelling develops.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Levofloxacin 的其他交互作用
Betamethasone 的其他交互作用
常見問題
Can I take Betamethasone with Levofloxacin?
MediHelp rates the interaction as major. Betamethasone and Levofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Using a fluoroquinolone together with a systemic corticosteroid increases the risk of tendinitis and tendon rupture, particularly of the Achilles tendon. The risk is higher in older adults and transplant patients.
How serious is the interaction between Betamethasone and Levofloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, especially in patients over 60. Stop levofloxacin and rest the limb if tendon pain or swelling develops.
What other medicines interact with Levofloxacin?
MediHelp also lists interactions of Levofloxacin with, for example, Dronedarone, Ibutilide, Thioridazine. The full list is on the Levofloxacin page.
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