藥物交互作用
Betamethasone + Moxifloxacin
嚴重程度: 嚴重
Betamethasone and Moxifloxacin: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Concurrent corticosteroids and fluoroquinolones increase the risk of tendinitis and tendon rupture, notably of the Achilles tendon. Risk is higher in older patients, transplant recipients and those on prolonged or high-dose steroids.
用白話說明這項交互作用的意義
Betamethasone and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Betamethasone belongs to Endocrine; Moxifloxacin belongs to Anti Bacterial.
為什麼會發生
Both drugs damage tendon tissue and impair collagen turnover, producing additive tendon toxicity.
處置方式
Avoid the combination where possible, especially in patients over 60. Instruct patients to stop moxifloxacin and rest at the first sign of tendon pain or swelling.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Moxifloxacin 的其他交互作用
Betamethasone 的其他交互作用
常見問題
Can I take Betamethasone with Moxifloxacin?
MediHelp rates the interaction as major. Betamethasone and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Concurrent corticosteroids and fluoroquinolones increase the risk of tendinitis and tendon rupture, notably of the Achilles tendon. Risk is higher in older patients, transplant recipients and those on prolonged or high-dose steroids.
How serious is the interaction between Betamethasone and Moxifloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, especially in patients over 60. Instruct patients to stop moxifloxacin and rest at the first sign of tendon pain or swelling.
What other medicines interact with Moxifloxacin?
MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
