藥物交互作用
Betrixaban + Clopidogrel
嚴重程度: 嚴重
Betrixaban and Clopidogrel: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Betrixaban, a factor Xa inhibitor, combined with clopidogrel raises the risk of bleeding because the two drugs act on different parts of hemostasis. Clopidogrel does not materially change betrixaban levels.
用白話說明這項交互作用的意義
Betrixaban and Clopidogrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive pharmacodynamic effect of factor Xa inhibition and P2Y12 platelet inhibition.
處置方式
Combine only if clearly indicated and review the need regularly. Monitor for bleeding and hemoglobin, and consider gastroprotection.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Clopidogrel 的其他交互作用
常見問題
Can I take Betrixaban with Clopidogrel?
MediHelp rates the interaction as major. Betrixaban and Clopidogrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Betrixaban, a factor Xa inhibitor, combined with clopidogrel raises the risk of bleeding because the two drugs act on different parts of hemostasis. Clopidogrel does not materially change betrixaban levels.
How serious is the interaction between Betrixaban and Clopidogrel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Combine only if clearly indicated and review the need regularly. Monitor for bleeding and hemoglobin, and consider gastroprotection.
What other medicines interact with Clopidogrel?
MediHelp also lists interactions of Clopidogrel with, for example, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Abrocitinib, Acetylsalicylic acid. The full list is on the Clopidogrel page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
