藥物交互作用
Bexagliflozin + Glimepiride
嚴重程度: 中度
Bexagliflozin and Glimepiride: moderate interaction.
最後更新
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摘要
Bexagliflozin lowers glucose independently of insulin, and combined with a sulfonylurea it raises the risk of hypoglycemia. The risk is greater with higher sulfonylurea doses.
用白話說明這項交互作用的意義
Bexagliflozin and Glimepiride can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bexagliflozin belongs to Endocrine; Glimepiride belongs to Endocrine.
為什麼會發生
Additive glucose-lowering effects of SGLT2 inhibition and sulfonylurea-stimulated insulin secretion.
處置方式
Consider lowering the glimepiride dose when bexagliflozin is started. Monitor blood glucose and counsel patients on hypoglycemia symptoms.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Glimepiride 的其他交互作用
Bexagliflozin 的其他交互作用
常見問題
Can I take Bexagliflozin with Glimepiride?
MediHelp rates the interaction as moderate. Bexagliflozin and Glimepiride can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bexagliflozin lowers glucose independently of insulin, and combined with a sulfonylurea it raises the risk of hypoglycemia. The risk is greater with higher sulfonylurea doses.
How serious is the interaction between Bexagliflozin and Glimepiride?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider lowering the glimepiride dose when bexagliflozin is started. Monitor blood glucose and counsel patients on hypoglycemia symptoms.
What other medicines interact with Glimepiride?
MediHelp also lists interactions of Glimepiride with, for example, Fluconazole, Insulin degludec-liraglutide, Insulin glargine-lixisenatide. The full list is on the Glimepiride page.
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