藥物交互作用
Bexagliflozin + Glipizide-metformin
嚴重程度: 中度
Bexagliflozin and Glipizide-metformin: moderate interaction.
最後更新
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摘要
Bexagliflozin adds glucose-lowering effect to glipizide, which raises the risk of hypoglycemia. It also promotes volume depletion, which matters in patients on metformin.
用白話說明這項交互作用的意義
Bexagliflozin and Glipizide-metformin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bexagliflozin belongs to Endocrine; Glipizide-metformin belongs to Endocrine.
為什麼會發生
Additive glucose lowering from SGLT2 inhibition and insulin secretagogue action.
處置方式
Consider reducing the glipizide dose when starting bexagliflozin and monitor blood glucose and hydration status.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Glipizide-metformin 的其他交互作用
Bexagliflozin 的其他交互作用
常見問題
Can I take Bexagliflozin with Glipizide-metformin?
MediHelp rates the interaction as moderate. Bexagliflozin and Glipizide-metformin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bexagliflozin adds glucose-lowering effect to glipizide, which raises the risk of hypoglycemia. It also promotes volume depletion, which matters in patients on metformin.
How serious is the interaction between Bexagliflozin and Glipizide-metformin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider reducing the glipizide dose when starting bexagliflozin and monitor blood glucose and hydration status.
What other medicines interact with Glipizide-metformin?
MediHelp also lists interactions of Glipizide-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Glipizide-metformin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
