藥物交互作用
Bexagliflozin + Gliclazide
嚴重程度: 中度
Bexagliflozin and Gliclazide: moderate interaction.
最後更新
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摘要
SGLT2 inhibitors combined with insulin secretagogues such as gliclazide raise the risk of hypoglycemia. The glucose-lowering effects are additive.
用白話說明這項交互作用的意義
Bexagliflozin and Gliclazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bexagliflozin belongs to Endocrine; Gliclazide belongs to Endocrine.
為什麼會發生
Additive glucose lowering: urinary glucose excretion plus stimulated insulin secretion.
處置方式
Consider reducing the gliclazide dose when starting bexagliflozin, and monitor blood glucose.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Gliclazide 的其他交互作用
Bexagliflozin 的其他交互作用
常見問題
Can I take Bexagliflozin with Gliclazide?
MediHelp rates the interaction as moderate. Bexagliflozin and Gliclazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. SGLT2 inhibitors combined with insulin secretagogues such as gliclazide raise the risk of hypoglycemia. The glucose-lowering effects are additive.
How serious is the interaction between Bexagliflozin and Gliclazide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider reducing the gliclazide dose when starting bexagliflozin, and monitor blood glucose.
What other medicines interact with Gliclazide?
MediHelp also lists interactions of Gliclazide with, for example, Ciprofloxacin, Clarithromycin, Disopyramide. The full list is on the Gliclazide page.
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