藥物交互作用
Bictegravir + Ferrous gluconate
嚴重程度: 中度
Bictegravir and Ferrous gluconate: moderate interaction.
最後更新
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摘要
Iron binds bictegravir in the gut and can lower its exposure when taken fasting. Reduced levels may lead to loss of HIV virologic suppression or resistance.
用白話說明這項交互作用的意義
Bictegravir and Ferrous gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Iron cations chelate bictegravir in the gastrointestinal tract, reducing absorption.
處置方式
Take bictegravir and iron together with food, or take bictegravir at least 2 hours before iron when fasting. Do not take iron within 2 hours before bictegravir on an empty stomach.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Ferrous gluconate 的其他交互作用
常見問題
Can I take Bictegravir with Ferrous gluconate?
MediHelp rates the interaction as moderate. Bictegravir and Ferrous gluconate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron binds bictegravir in the gut and can lower its exposure when taken fasting. Reduced levels may lead to loss of HIV virologic suppression or resistance.
How serious is the interaction between Bictegravir and Ferrous gluconate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take bictegravir and iron together with food, or take bictegravir at least 2 hours before iron when fasting. Do not take iron within 2 hours before bictegravir on an empty stomach.
What other medicines interact with Ferrous gluconate?
MediHelp also lists interactions of Ferrous gluconate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous gluconate page.
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