藥物交互作用
Ciprofloxacin + Ferrous gluconate
嚴重程度: 嚴重
Ciprofloxacin and Ferrous gluconate: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Oral iron binds ciprofloxacin in the gut and markedly reduces its absorption. This can lower antibiotic concentrations enough to cause treatment failure and promote resistance.
用白話說明這項交互作用的意義
Ciprofloxacin and Ferrous gluconate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ciprofloxacin belongs to Anti Bacterial; Ferrous gluconate belongs to Miscellaneous.
為什麼會發生
Ferrous iron chelates ciprofloxacin in the gastrointestinal tract, forming poorly absorbed complexes.
處置方式
Give oral ciprofloxacin at least 2 hours before or 6 hours after iron. Use an alternative if separation is not practical.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Ciprofloxacin 的其他交互作用
Ferrous gluconate 的其他交互作用
常見問題
Can I take Ciprofloxacin with Ferrous gluconate?
MediHelp rates the interaction as major. Ciprofloxacin and Ferrous gluconate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral iron binds ciprofloxacin in the gut and markedly reduces its absorption. This can lower antibiotic concentrations enough to cause treatment failure and promote resistance.
How serious is the interaction between Ciprofloxacin and Ferrous gluconate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ciprofloxacin at least 2 hours before or 6 hours after iron. Use an alternative if separation is not practical.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
