藥物交互作用
Buprenorphine subdermal implant + Scopolamine
嚴重程度: 嚴重
Buprenorphine subdermal implant and Scopolamine: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
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摘要
Buprenorphine is an opioid with sedative and respiratory depressant effects, and scopolamine adds central sedation. The combination can increase drowsiness, cognitive impairment and the risk of respiratory depression.
用白話說明這項交互作用的意義
Buprenorphine subdermal implant and Scopolamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive CNS depression from opioid partial agonism and central antimuscarinic activity.
處置方式
Use only if no alternative is adequate and monitor for excessive sedation and slowed breathing. Counsel the patient about impaired alertness, especially after scopolamine is started.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Scopolamine 的其他交互作用
常見問題
Can I take Buprenorphine subdermal implant with Scopolamine?
MediHelp rates the interaction as major. Buprenorphine subdermal implant and Scopolamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Buprenorphine is an opioid with sedative and respiratory depressant effects, and scopolamine adds central sedation. The combination can increase drowsiness, cognitive impairment and the risk of respiratory depression.
How serious is the interaction between Buprenorphine subdermal implant and Scopolamine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use only if no alternative is adequate and monitor for excessive sedation and slowed breathing. Counsel the patient about impaired alertness, especially after scopolamine is started.
What other medicines interact with Scopolamine?
MediHelp also lists interactions of Scopolamine with, for example, Benzhydrocodone / acetaminophen, Buprenorphine long-acting, Buprenorphine transdermal. The full list is on the Scopolamine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
