藥物交互作用
Fentanyl iontophoretic transdermal system + Scopolamine
嚴重程度: 嚴重
Fentanyl iontophoretic transdermal system and Scopolamine: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Fentanyl delivered by an iontophoretic system is a potent opioid with sedative and respiratory depressant effects. Scopolamine can add to drowsiness and cognitive impairment, increasing the risk of dangerous CNS depression.
用白話說明這項交互作用的意義
Fentanyl iontophoretic transdermal system and Scopolamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive CNS and respiratory depression from opioid agonism and central antimuscarinic effects.
處置方式
Avoid the combination where possible and choose a non-sedating alternative to scopolamine. If used together, monitor sedation and respiratory status closely.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Scopolamine 的其他交互作用
常見問題
Can I take Fentanyl iontophoretic transdermal system with Scopolamine?
MediHelp rates the interaction as major. Fentanyl iontophoretic transdermal system and Scopolamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Fentanyl delivered by an iontophoretic system is a potent opioid with sedative and respiratory depressant effects. Scopolamine can add to drowsiness and cognitive impairment, increasing the risk of dangerous CNS depression.
How serious is the interaction between Fentanyl iontophoretic transdermal system and Scopolamine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible and choose a non-sedating alternative to scopolamine. If used together, monitor sedation and respiratory status closely.
What other medicines interact with Scopolamine?
MediHelp also lists interactions of Scopolamine with, for example, Benzhydrocodone / acetaminophen, Buprenorphine long-acting, Buprenorphine subdermal implant. The full list is on the Scopolamine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
