藥物交互作用
Butabarbital + Voriconazole
嚴重程度: 禁忌併用
Butabarbital and Voriconazole: contraindicated interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Butabarbital, a barbiturate, is expected to lower voriconazole levels, risking subtherapeutic antifungal exposure and treatment failure.
用白話說明這項交互作用的意義
Butabarbital and Voriconazole are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Barbiturate-mediated induction of CYP2C19 and CYP3A4 enhances voriconazole metabolism.
處置方式
Avoid combination; use a non-barbiturate sedative. If it cannot be avoided, monitor voriconazole trough concentrations and clinical response.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Voriconazole 的其他交互作用
常見問題
Can I take Butabarbital with Voriconazole?
MediHelp rates the interaction as contraindicated. Butabarbital and Voriconazole are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Butabarbital, a barbiturate, is expected to lower voriconazole levels, risking subtherapeutic antifungal exposure and treatment failure.
How serious is the interaction between Butabarbital and Voriconazole?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combination; use a non-barbiturate sedative. If it cannot be avoided, monitor voriconazole trough concentrations and clinical response.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Carbamazepine, Conivaptan. The full list is on the Voriconazole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
