藥物交互作用
Calcium / magnesium / potassium / sodium oxybates + Cyclizine
嚴重程度: 嚴重
Calcium / magnesium / potassium / sodium oxybates and Cyclizine: major interaction.
最後更新
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摘要
Oxybate salts cause marked CNS and respiratory depression, and cyclizine is a sedating antihistamine. Combined use can result in profound sedation, respiratory depression, coma and death.
用白話說明這項交互作用的意義
Calcium / magnesium / potassium / sodium oxybates and Cyclizine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive CNS and respiratory depression through pharmacodynamic synergism.
處置方式
Avoid concurrent use where alternatives exist; if unavoidable, use the lowest effective doses and monitor closely for sedation and respiratory depression.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Cyclizine 的其他交互作用
常見問題
Can I take Calcium / magnesium / potassium / sodium oxybates with Cyclizine?
MediHelp rates the interaction as major. Calcium / magnesium / potassium / sodium oxybates and Cyclizine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oxybate salts cause marked CNS and respiratory depression, and cyclizine is a sedating antihistamine. Combined use can result in profound sedation, respiratory depression, coma and death.
How serious is the interaction between Calcium / magnesium / potassium / sodium oxybates and Cyclizine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where alternatives exist; if unavoidable, use the lowest effective doses and monitor closely for sedation and respiratory depression.
What other medicines interact with Cyclizine?
MediHelp also lists interactions of Cyclizine with, for example, Henbane, Sodium oxybate, Abobotulinumtoxina. The full list is on the Cyclizine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
