藥物交互作用
Cyclizine + Henbane
嚴重程度: 嚴重
Cyclizine and Henbane: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Henbane contains the antimuscarinic alkaloids hyoscyamine and scopolamine. Together with cyclizine, anticholinergic effects such as dry mouth, tachycardia, urinary retention, confusion and hyperthermia can be intensified, with toxicity possible given the variable alkaloid content.
用白話說明這項交互作用的意義
Cyclizine and Henbane can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive muscarinic receptor antagonism.
處置方式
Avoid using henbane with cyclizine. If exposure has occurred, monitor for anticholinergic toxicity and treat supportively.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Cyclizine 的其他交互作用
常見問題
Can I take Cyclizine with Henbane?
MediHelp rates the interaction as major. Cyclizine and Henbane can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Henbane contains the antimuscarinic alkaloids hyoscyamine and scopolamine. Together with cyclizine, anticholinergic effects such as dry mouth, tachycardia, urinary retention, confusion and hyperthermia can be intensified, with toxicity possible given the variable alkaloid content.
How serious is the interaction between Cyclizine and Henbane?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using henbane with cyclizine. If exposure has occurred, monitor for anticholinergic toxicity and treat supportively.
What other medicines interact with Cyclizine?
MediHelp also lists interactions of Cyclizine with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Abobotulinumtoxina. The full list is on the Cyclizine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
