藥物交互作用
Cangrelor + Warfarin
嚴重程度: 中度
Cangrelor and Warfarin: moderate interaction.
最後更新
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摘要
Cangrelor is an intravenous P2Y12 inhibitor with a very short action. With warfarin, bleeding risk increases while it is infused, because platelet and coagulation pathways are both inhibited.
用白話說明這項交互作用的意義
Cangrelor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cangrelor belongs to Cardiovascular; Warfarin belongs to Cardiovascular.
為什麼會發生
Additive pharmacodynamic effect of P2Y12 platelet inhibition and vitamin K antagonist anticoagulation.
處置方式
Monitor for bleeding and hemoglobin during and after the infusion, and check INR as needed. Reassess the need for combined antithrombotic therapy.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Warfarin 的其他交互作用
Cangrelor 的其他交互作用
常見問題
Can I take Cangrelor with Warfarin?
MediHelp rates the interaction as moderate. Cangrelor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cangrelor is an intravenous P2Y12 inhibitor with a very short action. With warfarin, bleeding risk increases while it is infused, because platelet and coagulation pathways are both inhibited.
How serious is the interaction between Cangrelor and Warfarin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and hemoglobin during and after the infusion, and check INR as needed. Reassess the need for combined antithrombotic therapy.
What other medicines interact with Warfarin?
MediHelp also lists interactions of Warfarin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Warfarin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。