藥品參考
Cangrelor
Cangrelor is a medicine in the class cardiovascular. It is used for coronary artery stent thrombosis.
- 藥物類別: Cardiovascular
- 用途: coronary artery stent thrombosis
最後更新 來源: US FDA label
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Cardiovascular
- 常見劑型
- 注射劑
- 常見規格
- 50 mg
- 已知交互作用
- 3 (嚴重: 2 · 中度: 1)
- 商品名
- 2
- 國家與市場
- 2
用途
作用方式
Direct P2Y12 platelet receptor inhibitor that blocks ADP-induced platelet activation and aggregation; binds selectively and reversibly to the P2Y12 receptor.
成人常用劑量（仿單摘要）
Adjunct to PCI: 30 mcg/kg IV bolus before PCI, followed immediately by 4 mcg/kg/min IV infusion for at least 2 hours or the duration of PCI, whichever is longer.
懷孕與哺乳
- 懷孕
- Unknown No human data. Animal studies showed no malformations, but fetal growth retardation and increased abortion/intrauterine losses occurred at higher doses. May increase maternal bleeding during labor and delivery.
- 哺乳
- Unknown No data on presence in milk; exposure in the breastfed infant is expected to be very low due to short half-life.
已通報的副作用
- Bleeding
- Dyspnea
- Hypersensitivity reactions (anaphylaxis, bronchospasm, angioedema, stridor)
- Worsening renal function in severe renal impairment
禁忌症
- Significant active bleeding.
- Known hypersensitivity (e.g., anaphylaxis) to cangrelor or any component of the product.
哪些人需要特別留意
- Bleeding risk: P2Y12 inhibitors including cangrelor increase bleeding risk; bleeding events of all severities were more common than with clopidogrel. No antiplatelet effect after an hour once discontinued.
- Neuraxial blockade is not advised during use because of potential spinal hematoma risk; discontinue 1 hour before labor, delivery, or neuraxial blockade when possible.
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (3)
- Cangrelor + Clopidogrel Major
- Cangrelor + Prasugrel Major
- Cangrelor + Warfarin Moderate
同類別的其他藥品
常見問題
What is Cangrelor used for?
Cangrelor is a medicine in the class cardiovascular. It is used for Coronary artery stent thrombosis, Myocardial infarction.
What side effects have been reported with Cangrelor?
Bleeding, Dyspnea, Hypersensitivity reactions (anaphylaxis, bronchospasm, angioedema, stridor), Worsening renal function in severe renal impairment.
Can Cangrelor be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. No human data. Animal studies showed no malformations, but fetal growth retardation and increased abortion/intrauterine losses occurred at higher doses. May increase maternal bleeding during labor and delivery. Breastfeeding: Unknown. No data on presence in milk; exposure in the breastfed infant is expected to be very low due to short half-life.
What does Cangrelor interact with?
MediHelp lists 3 known interactions for Cangrelor. Major: 2 · Moderate: 1. The most serious include Clopidogrel, Prasugrel, Warfarin.
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