藥物交互作用
Ceftazidime + Sodium picosulfate / magnesium oxide / anhydrous citric acid
嚴重程度: 中度
Ceftazidime and Sodium picosulfate / magnesium oxide / anhydrous citric acid: moderate interaction.
最後更新
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摘要
Sodium picosulfate is a prodrug activated by colonic bacteria, so antibiotics that disrupt colonic flora may reduce its laxative effect. Parenteral ceftazidime reaches the colon less than oral antibiotics, but poor bowel cleansing before colonoscopy is possible.
用白話說明這項交互作用的意義
Ceftazidime and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Antibiotic suppression of colonic bacteria reduces conversion of picosulfate to its active metabolite.
處置方式
Assess bowel preparation adequacy and consider additional or alternative cleansing if the preparation seems inadequate. Where possible, avoid starting antibiotics during the preparation period.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Ceftazidime 的其他交互作用
常見問題
Can I take Ceftazidime with Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates the interaction as moderate. Ceftazidime and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium picosulfate is a prodrug activated by colonic bacteria, so antibiotics that disrupt colonic flora may reduce its laxative effect. Parenteral ceftazidime reaches the colon less than oral antibiotics, but poor bowel cleansing before colonoscopy is possible.
How serious is the interaction between Ceftazidime and Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess bowel preparation adequacy and consider additional or alternative cleansing if the preparation seems inadequate. Where possible, avoid starting antibiotics during the preparation period.
What other medicines interact with Ceftazidime?
MediHelp also lists interactions of Ceftazidime with, for example, Amikacin, Cholera vaccine, Dexamethasone-tobramycin. The full list is on the Ceftazidime page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
