藥物交互作用
Citric acid / glucono-delta-lactone / magnesium carbonate + Misoprostol
嚴重程度: 中度
Citric acid / glucono-delta-lactone / magnesium carbonate and Misoprostol: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Magnesium-containing preparations can aggravate the diarrhea that is the most common adverse effect of misoprostol. Antacid use may also modestly lower systemic exposure to misoprostol acid.
用白話說明這項交互作用的意義
Citric acid / glucono-delta-lactone / magnesium carbonate and Misoprostol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Additive osmotic laxative effect of magnesium with misoprostol-induced intestinal secretion and motility, plus possible reduced absorption of the active acid.
處置方式
Prefer an aluminum- or calcium-based antacid without magnesium if one is required. Monitor for diarrhea and dehydration.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Misoprostol 的其他交互作用
常見問題
Can I take Citric acid / glucono-delta-lactone / magnesium carbonate with Misoprostol?
MediHelp rates the interaction as moderate. Citric acid / glucono-delta-lactone / magnesium carbonate and Misoprostol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium-containing preparations can aggravate the diarrhea that is the most common adverse effect of misoprostol. Antacid use may also modestly lower systemic exposure to misoprostol acid.
How serious is the interaction between Citric acid / glucono-delta-lactone / magnesium carbonate and Misoprostol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prefer an aluminum- or calcium-based antacid without magnesium if one is required. Monitor for diarrhea and dehydration.
What other medicines interact with Misoprostol?
MediHelp also lists interactions of Misoprostol with, for example, Oxytocin, Aluminum hydroxide / magnesium carbonate, Aluminum hydroxide / magnesium trisilicate. The full list is on the Misoprostol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
