藥物交互作用
Clomipramine + Dopamine
嚴重程度: 嚴重
Clomipramine and Dopamine: major interaction.
最後更新
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摘要
Clomipramine can potentiate pressor and arrhythmogenic effects of sympathomimetics by blocking catecholamine reuptake. Dopamine responses may be exaggerated or unpredictable.
用白話說明這項交互作用的意義
Clomipramine and Dopamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Clomipramine belongs to Central Nervous System; Dopamine belongs to Cardiovascular.
為什麼會發生
Inhibition of norepinephrine reuptake by clomipramine alters response to dopamine.
處置方式
Use low initial dopamine doses with continuous blood pressure and ECG monitoring.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Dopamine 的其他交互作用
Clomipramine 的其他交互作用
常見問題
Can I take Clomipramine with Dopamine?
MediHelp rates the interaction as major. Clomipramine and Dopamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Clomipramine can potentiate pressor and arrhythmogenic effects of sympathomimetics by blocking catecholamine reuptake. Dopamine responses may be exaggerated or unpredictable.
How serious is the interaction between Clomipramine and Dopamine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use low initial dopamine doses with continuous blood pressure and ECG monitoring.
What other medicines interact with Dopamine?
MediHelp also lists interactions of Dopamine with, for example, Dihydroergotamine intranasal, Dihydroergotamine, Selegiline transdermal. The full list is on the Dopamine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
