藥物交互作用
Colchicine + Teduglutide
嚴重程度: 中度
Colchicine and Teduglutide: moderate interaction.
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摘要
Teduglutide increases intestinal fluid absorption and may enhance absorption of oral drugs. For colchicine, a narrow therapeutic index drug, higher exposure is possible and could increase toxicity.
用白話說明這項交互作用的意義
Colchicine and Teduglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colchicine belongs to Genitourinary; Teduglutide belongs to Endocrine.
為什麼會發生
Teduglutide improves intestinal absorptive function and fluid uptake, which may increase absorption of oral colchicine.
處置方式
Monitor for signs of colchicine toxicity (diarrhea, nausea, muscle weakness) when starting teduglutide and adjust the colchicine dose if needed.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Colchicine 的其他交互作用
Teduglutide 的其他交互作用
常見問題
Can I take Colchicine with Teduglutide?
MediHelp rates the interaction as moderate. Colchicine and Teduglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Teduglutide increases intestinal fluid absorption and may enhance absorption of oral drugs. For colchicine, a narrow therapeutic index drug, higher exposure is possible and could increase toxicity.
How serious is the interaction between Colchicine and Teduglutide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of colchicine toxicity (diarrhea, nausea, muscle weakness) when starting teduglutide and adjust the colchicine dose if needed.
What other medicines interact with Colchicine?
MediHelp also lists interactions of Colchicine with, for example, Clarithromycin, Cobicistat, Cyclosporine. The full list is on the Colchicine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
