藥物交互作用
Cyclosporin + Ixekizumab
嚴重程度: 輕微
Cyclosporin and Ixekizumab: minor interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Reduced inflammation during IL-17A blockade may restore CYP450 activity that was suppressed by cytokines, theoretically lowering cyclosporine concentrations. A clinically important effect has not been established. Combined immunosuppression also raises infection concerns.
用白話說明這項交互作用的意義
Cyclosporin and Ixekizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cyclosporin belongs to Miscellaneous; Ixekizumab belongs to Miscellaneous.
為什麼會發生
Cytokine normalization may modestly increase CYP-mediated cyclosporine metabolism; this is theoretical.
處置方式
Check cyclosporine trough levels and clinical response when ixekizumab is started or stopped. Monitor for infection.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Cyclosporin 的其他交互作用
Ixekizumab 的其他交互作用
常見問題
Can I take Cyclosporin with Ixekizumab?
MediHelp rates the interaction as minor. Cyclosporin and Ixekizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reduced inflammation during IL-17A blockade may restore CYP450 activity that was suppressed by cytokines, theoretically lowering cyclosporine concentrations. A clinically important effect has not been established. Combined immunosuppression also raises infection concerns.
How serious is the interaction between Cyclosporin and Ixekizumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check cyclosporine trough levels and clinical response when ixekizumab is started or stopped. Monitor for infection.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。