藥物交互作用
Ixekizumab + Lomustine
嚴重程度: 中度
Ixekizumab and Lomustine: moderate interaction.
最後更新
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摘要
Lomustine causes myelosuppression and immune suppression, while ixekizumab blocks IL-17A signaling and impairs host defense. Together they may raise the risk of serious bacterial, fungal or opportunistic infections.
用白話說明這項交互作用的意義
Ixekizumab and Lomustine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ixekizumab belongs to Miscellaneous; Lomustine belongs to Oncology.
為什麼會發生
Additive immunosuppression: cytotoxic marrow suppression plus IL-17A antagonism.
處置方式
Screen for active infection before and during therapy and monitor neutrophil counts. Hold ixekizumab if a serious infection develops.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Lomustine 的其他交互作用
- Adenovirus types 4 and 7 live + Lomustine 禁忌併用
- Bcg vaccine live + Lomustine 禁忌併用
- Influenza virus vaccine quadrivalent intranasal + Lomustine 禁忌併用
- Lomustine + Measles mumps and rubella vaccine 禁忌併用
- Lomustine + Measles mumps and rubella vaccine live 禁忌併用
- Lomustine + Measles mumps rubella and varicella vaccine live 禁忌併用
Ixekizumab 的其他交互作用
常見問題
Can I take Ixekizumab with Lomustine?
MediHelp rates the interaction as moderate. Ixekizumab and Lomustine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lomustine causes myelosuppression and immune suppression, while ixekizumab blocks IL-17A signaling and impairs host defense. Together they may raise the risk of serious bacterial, fungal or opportunistic infections.
How serious is the interaction between Ixekizumab and Lomustine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Screen for active infection before and during therapy and monitor neutrophil counts. Hold ixekizumab if a serious infection develops.
What other medicines interact with Lomustine?
MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Lomustine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
