藥物交互作用
Desogestrel-ethinyl estradiol + Enasidenib
嚴重程度: 中度
Desogestrel-ethinyl estradiol and Enasidenib: moderate interaction.
最後更新
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摘要
Enasidenib may alter concentrations of combined hormonal contraceptives, and the direction of the change is uncertain. Contraceptive reliability could be affected during a pregnancy-sensitive treatment.
用白話說明這項交互作用的意義
Desogestrel-ethinyl estradiol and Enasidenib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Desogestrel-ethinyl estradiol belongs to Endocrine; Enasidenib belongs to Oncology.
為什麼會發生
Mechanism is not established; enasidenib may modulate CYP enzymes involved in hormone metabolism.
處置方式
Advise an additional non-hormonal contraceptive method during enasidenib treatment. Monitor for bleeding pattern changes.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Desogestrel-ethinyl estradiol 的其他交互作用
Enasidenib 的其他交互作用
常見問題
Can I take Desogestrel-ethinyl estradiol with Enasidenib?
MediHelp rates the interaction as moderate. Desogestrel-ethinyl estradiol and Enasidenib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Enasidenib may alter concentrations of combined hormonal contraceptives, and the direction of the change is uncertain. Contraceptive reliability could be affected during a pregnancy-sensitive treatment.
How serious is the interaction between Desogestrel-ethinyl estradiol and Enasidenib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise an additional non-hormonal contraceptive method during enasidenib treatment. Monitor for bleeding pattern changes.
What other medicines interact with Desogestrel-ethinyl estradiol?
MediHelp also lists interactions of Desogestrel-ethinyl estradiol with, for example, Fezolinetant, Aminocaproic acid, Amobarbital. The full list is on the Desogestrel-ethinyl estradiol page.
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