藥物交互作用
Dexamethasone + Yellow fever vaccine
嚴重程度: 禁忌併用
Dexamethasone and Yellow fever vaccine: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Yellow fever vaccine is a live attenuated virus vaccine. In patients on immunosuppressive doses of dexamethasone it may cause serious vaccine-associated disease, and immunity may be inadequate.
用白話說明這項交互作用的意義
Dexamethasone and Yellow fever vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Glucocorticoid-induced immunosuppression impairs control of attenuated virus replication and blunts the immune response.
處置方式
Avoid vaccination during immunosuppressive corticosteroid therapy and for about 1 month after stopping. If travel to an endemic area cannot be avoided, seek a specialist assessment and consider a medical exemption letter.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Dexamethasone 的其他交互作用
常見問題
Can I take Dexamethasone with Yellow fever vaccine?
MediHelp rates the interaction as contraindicated. Dexamethasone and Yellow fever vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Yellow fever vaccine is a live attenuated virus vaccine. In patients on immunosuppressive doses of dexamethasone it may cause serious vaccine-associated disease, and immunity may be inadequate.
How serious is the interaction between Dexamethasone and Yellow fever vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid vaccination during immunosuppressive corticosteroid therapy and for about 1 month after stopping. If travel to an endemic area cannot be avoided, seek a specialist assessment and consider a medical exemption letter.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
