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藥物交互作用

Dextroamphetamine transdermal + Vitamin c

嚴重程度: 中度

Dextroamphetamine transdermal and Vitamin c: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Ascorbic acid in large doses can acidify the urine, which increases renal excretion of amphetamines and may reduce their effect. The effect is most relevant with high-dose vitamin C.

用白話說明這項交互作用的意義

Dextroamphetamine transdermal and Vitamin c can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

證據等級: Moderate

為什麼會發生

Urinary acidification ionizes amphetamine and reduces renal tubular reabsorption, increasing clearance.

處置方式

Avoid high-dose vitamin C or acidifying agents during amphetamine therapy. Reassess clinical response and adjust the dose if needed.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Dextroamphetamine transdermal with Vitamin c?

MediHelp rates the interaction as moderate. Dextroamphetamine transdermal and Vitamin c can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ascorbic acid in large doses can acidify the urine, which increases renal excretion of amphetamines and may reduce their effect. The effect is most relevant with high-dose vitamin C.

How serious is the interaction between Dextroamphetamine transdermal and Vitamin c?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid high-dose vitamin C or acidifying agents during amphetamine therapy. Reassess clinical response and adjust the dose if needed.

What other medicines interact with Vitamin c?

MediHelp also lists interactions of Vitamin c with, for example, Deferoxamine, Aluminum hydroxide, Aspirin / citric acid / sodium bicarbonate. The full list is on the Vitamin c page.

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