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藥物交互作用

Diflunisal + Ketorolac

嚴重程度: 禁忌併用

Diflunisal and Ketorolac: contraindicated interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Ketorolac is contraindicated with other NSAIDs, and diflunisal is an NSAID. Combined use increases the risk of gastrointestinal bleeding and ulceration, renal injury and platelet dysfunction without added analgesia.

用白話說明這項交互作用的意義

Diflunisal and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Diflunisal belongs to Musculoskeletal; Ketorolac belongs to Musculoskeletal.

證據等級: High

為什麼會發生

Additive NSAID toxicity (GI, renal, antiplatelet)

處置方式

Do not use two NSAIDs together; give ketorolac as the sole NSAID and for no longer than 5 days.

可向藥師詢問的問題

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用，即可解鎖 Diflunisal 與 Ketorolac 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription
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常見問題

Can I take Diflunisal with Ketorolac?

MediHelp rates the interaction as contraindicated. Diflunisal and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac is contraindicated with other NSAIDs, and diflunisal is an NSAID. Combined use increases the risk of gastrointestinal bleeding and ulceration, renal injury and platelet dysfunction without added analgesia.

How serious is the interaction between Diflunisal and Ketorolac?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use two NSAIDs together; give ketorolac as the sole NSAID and for no longer than 5 days.

What other medicines interact with Diflunisal?

MediHelp also lists interactions of Diflunisal with, for example, Ketorolac intranasal, Acemetacin, Acetazolamide. The full list is on the Diflunisal page.

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