藥物交互作用
Docusate + Mineral oil
嚴重程度: 中度
Docusate and Mineral oil: moderate interaction.
最後更新
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摘要
Docusate is a surfactant that may increase absorption of mineral oil from the gut. Absorbed mineral oil can deposit in tissues and, rarely, cause lipoid pneumonia or granulomas, so the combination is generally discouraged.
用白話說明這項交互作用的意義
Docusate and Mineral oil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Docusate belongs to Gastrointestinal Tract; Mineral oil belongs to Gastrointestinal Tract.
為什麼會發生
Docusate's surfactant action emulsifies mineral oil and enhances its intestinal absorption.
處置方式
Avoid combining the two laxatives. Use another stool softener or laxative if mineral oil is needed, especially in patients at risk of aspiration.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Mineral oil 的其他交互作用
常見問題
Can I take Docusate with Mineral oil?
MediHelp rates the interaction as moderate. Docusate and Mineral oil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Docusate is a surfactant that may increase absorption of mineral oil from the gut. Absorbed mineral oil can deposit in tissues and, rarely, cause lipoid pneumonia or granulomas, so the combination is generally discouraged.
How serious is the interaction between Docusate and Mineral oil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining the two laxatives. Use another stool softener or laxative if mineral oil is needed, especially in patients at risk of aspiration.
What other medicines interact with Mineral oil?
MediHelp also lists interactions of Mineral oil with, for example, Vitamin k1, Beta carotene, Cholecalciferol. The full list is on the Mineral oil page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。