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藥物交互作用

Mineral oil + Vitamin k1

嚴重程度: 中度

Mineral oil and Vitamin k1: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Chronic mineral oil use can reduce absorption of phytonadione and other fat-soluble vitamins, which may lead to hypoprothrombinemia and bleeding in susceptible patients, such as those on anticoagulants or with poor intake.

用白話說明這項交互作用的意義

Mineral oil and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Mineral oil belongs to Gastrointestinal Tract; Vitamin k1 belongs to Cardiovascular.

證據等級: Moderate

為什麼會發生

Mineral oil dissolves vitamin K in the gut lumen and carries it out in the stool, reducing absorption.

處置方式

Avoid regular mineral oil use in patients dependent on vitamin K status. Monitor INR if the patient is on warfarin or has risk factors for deficiency.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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建立帳號並開始 Pro+ 試用,即可解鎖 Mineral oil 與 Vitamin k1 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Mineral oil with Vitamin k1?

MediHelp rates the interaction as moderate. Mineral oil and Vitamin k1 can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Chronic mineral oil use can reduce absorption of phytonadione and other fat-soluble vitamins, which may lead to hypoprothrombinemia and bleeding in susceptible patients, such as those on anticoagulants or with poor intake.

How serious is the interaction between Mineral oil and Vitamin k1?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular mineral oil use in patients dependent on vitamin K status. Monitor INR if the patient is on warfarin or has risk factors for deficiency.

What other medicines interact with Mineral oil?

MediHelp also lists interactions of Mineral oil with, for example, Docusate, Beta carotene, Cholecalciferol. The full list is on the Mineral oil page.

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