藥物交互作用
Ethotoin + Folic acid
嚴重程度: 中度
Ethotoin and Folic acid: moderate interaction.
最後更新
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摘要
Folic acid, particularly at high doses, may lower serum levels of hydantoin anticonvulsants and could reduce seizure control. This is described mainly for phenytoin and is extrapolated to ethotoin.
用白話說明這項交互作用的意義
Ethotoin and Folic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Folate may enhance hydantoin metabolism; the mechanism is not firmly established and is extrapolated from phenytoin.
處置方式
Monitor seizure control when starting or increasing folic acid. Check anticonvulsant levels if breakthrough seizures occur.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Folic acid 的其他交互作用
常見問題
Can I take Ethotoin with Folic acid?
MediHelp rates the interaction as moderate. Ethotoin and Folic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Folic acid, particularly at high doses, may lower serum levels of hydantoin anticonvulsants and could reduce seizure control. This is described mainly for phenytoin and is extrapolated to ethotoin.
How serious is the interaction between Ethotoin and Folic acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor seizure control when starting or increasing folic acid. Check anticonvulsant levels if breakthrough seizures occur.
What other medicines interact with Folic acid?
MediHelp also lists interactions of Folic acid with, for example, Fosphenytoin, Glucarpidase, Methotrexate. The full list is on the Folic acid page.
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