藥物交互作用
Etodolac + Ketorolac intranasal
嚴重程度: 禁忌併用
Etodolac and Ketorolac intranasal: contraindicated interaction.
最後更新
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摘要
Using etodolac with intranasal ketorolac gives duplicate NSAID therapy, increasing the risk of gastrointestinal bleeding or ulceration, renal impairment and cardiovascular events. Intranasal ketorolac is systemically absorbed and carries the same prohibition on concurrent NSAIDs as the oral form.
用白話說明這項交互作用的意義
Etodolac and Ketorolac intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Additive cyclooxygenase inhibition producing additive gastrointestinal, renal, platelet and cardiovascular toxicity.
處置方式
Avoid the combination; use a single NSAID. Stop etodolac before starting ketorolac, or choose a non-NSAID analgesic.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Etodolac 的其他交互作用
常見問題
Can I take Etodolac with Ketorolac intranasal?
MediHelp rates the interaction as contraindicated. Etodolac and Ketorolac intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Using etodolac with intranasal ketorolac gives duplicate NSAID therapy, increasing the risk of gastrointestinal bleeding or ulceration, renal impairment and cardiovascular events. Intranasal ketorolac is systemically absorbed and carries the same prohibition on concurrent NSAIDs as the oral form.
How serious is the interaction between Etodolac and Ketorolac intranasal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; use a single NSAID. Stop etodolac before starting ketorolac, or choose a non-NSAID analgesic.
What other medicines interact with Etodolac?
MediHelp also lists interactions of Etodolac with, for example, Ketorolac, Aceclofenac, Acemetacin. The full list is on the Etodolac page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
