藥物交互作用
Everolimus + Influenza virus vaccine quadrivalent intranasal
嚴重程度: 禁忌併用
Everolimus and Influenza virus vaccine quadrivalent intranasal: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
The intranasal influenza vaccine contains live attenuated virus, which could replicate more extensively in a patient immunosuppressed by everolimus. Vaccine response may also be reduced. Live vaccines are generally avoided in patients on everolimus.
用白話說明這項交互作用的意義
Everolimus and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Everolimus-induced immunosuppression impairs control of live attenuated virus replication and reduces vaccine response.
處置方式
Do not give the live intranasal vaccine; use an inactivated injectable influenza vaccine instead.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Everolimus 的其他交互作用
常見問題
Can I take Everolimus with Influenza virus vaccine quadrivalent intranasal?
MediHelp rates the interaction as contraindicated. Everolimus and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which could replicate more extensively in a patient immunosuppressed by everolimus. Vaccine response may also be reduced. Live vaccines are generally avoided in patients on everolimus.
How serious is the interaction between Everolimus and Influenza virus vaccine quadrivalent intranasal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the live intranasal vaccine; use an inactivated injectable influenza vaccine instead.
What other medicines interact with Everolimus?
MediHelp also lists interactions of Everolimus with, for example, Bcg vaccine live, Levoketoconazole, Measles mumps and rubella vaccine live. The full list is on the Everolimus page.
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