藥物交互作用
Exenatide injectable + Insulin degludec-liraglutide
嚴重程度: 嚴重
Exenatide injectable and Insulin degludec-liraglutide: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Exenatide is a GLP-1 receptor agonist, and the combination product already contains liraglutide, so the two would duplicate therapy. Together they increase gastrointestinal adverse effects and the risk of hypoglycemia without added benefit.
用白話說明這項交互作用的意義
Exenatide injectable and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Therapeutic duplication of GLP-1 receptor agonism with additive glucose-lowering effects.
處置方式
Avoid using two GLP-1 receptor agonists together. Use only one agent and adjust the insulin dose if switching.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Insulin degludec-liraglutide 的其他交互作用
常見問題
Can I take Exenatide injectable with Insulin degludec-liraglutide?
MediHelp rates the interaction as major. Exenatide injectable and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Exenatide is a GLP-1 receptor agonist, and the combination product already contains liraglutide, so the two would duplicate therapy. Together they increase gastrointestinal adverse effects and the risk of hypoglycemia without added benefit.
How serious is the interaction between Exenatide injectable and Insulin degludec-liraglutide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid using two GLP-1 receptor agonists together. Use only one agent and adjust the insulin dose if switching.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
