藥物交互作用
Finerenone + Itraconazole
嚴重程度: 禁忌併用
Finerenone and Itraconazole: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Itraconazole substantially increases finerenone exposure. This raises the risk of hyperkalemia, hypotension and renal function decline.
用白話說明這項交互作用的意義
Finerenone and Itraconazole are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Finerenone belongs to Cardiovascular; Itraconazole belongs to Anti Fungals.
為什麼會發生
Strong CYP3A4 inhibition by itraconazole reduces finerenone metabolism.
處置方式
Do not combine. Withhold finerenone during itraconazole therapy and check potassium before restarting.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Itraconazole 的其他交互作用
Finerenone 的其他交互作用
常見問題
Can I take Finerenone with Itraconazole?
MediHelp rates the interaction as contraindicated. Finerenone and Itraconazole are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Itraconazole substantially increases finerenone exposure. This raises the risk of hyperkalemia, hypotension and renal function decline.
How serious is the interaction between Finerenone and Itraconazole?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine. Withhold finerenone during itraconazole therapy and check potassium before restarting.
What other medicines interact with Itraconazole?
MediHelp also lists interactions of Itraconazole with, for example, Alfuzosin, Alprazolam, Avanafil. The full list is on the Itraconazole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
