藥物交互作用
Finerenone + Ritonavir
嚴重程度: 禁忌併用
Finerenone and Ritonavir: contraindicated interaction.
最後更新
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摘要
Ritonavir strongly inhibits CYP3A4 and markedly raises finerenone exposure. This increases the risk of hyperkalemia, hypotension and renal function decline.
用白話說明這項交互作用的意義
Finerenone and Ritonavir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Finerenone belongs to Cardiovascular; Ritonavir belongs to Anti Virals.
為什麼會發生
Strong CYP3A4 inhibition by ritonavir reduces the oxidative metabolism of finerenone.
處置方式
Do not use finerenone with ritonavir or other strong CYP3A4 inhibitors. Choose an alternative antiretroviral or withhold finerenone while the inhibitor is needed.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Finerenone 的其他交互作用
Ritonavir 的其他交互作用
常見問題
Can I take Finerenone with Ritonavir?
MediHelp rates the interaction as contraindicated. Finerenone and Ritonavir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ritonavir strongly inhibits CYP3A4 and markedly raises finerenone exposure. This increases the risk of hyperkalemia, hypotension and renal function decline.
How serious is the interaction between Finerenone and Ritonavir?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use finerenone with ritonavir or other strong CYP3A4 inhibitors. Choose an alternative antiretroviral or withhold finerenone while the inhibitor is needed.
What other medicines interact with Finerenone?
MediHelp also lists interactions of Finerenone with, for example, Carbamazepine, Clarithromycin, Ensitrelvir. The full list is on the Finerenone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
