藥物交互作用
Finerenone + Posaconazole
嚴重程度: 禁忌併用
Finerenone and Posaconazole: contraindicated interaction.
最後更新
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摘要
Posaconazole substantially increases finerenone exposure, raising the risk of hyperkalemia and hypotension and worsening renal function.
用白話說明這項交互作用的意義
Finerenone and Posaconazole are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Finerenone belongs to Cardiovascular; Posaconazole belongs to Anti Fungals.
為什麼會發生
Posaconazole strongly inhibits CYP3A4, the main route of finerenone metabolism.
處置方式
Do not use together; labeling contraindicates strong CYP3A4 inhibitors. If antifungal therapy is needed, hold finerenone for the course and check potassium before restarting.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Posaconazole 的其他交互作用
Finerenone 的其他交互作用
常見問題
Can I take Finerenone with Posaconazole?
MediHelp rates the interaction as contraindicated. Finerenone and Posaconazole are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Posaconazole substantially increases finerenone exposure, raising the risk of hyperkalemia and hypotension and worsening renal function.
How serious is the interaction between Finerenone and Posaconazole?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; labeling contraindicates strong CYP3A4 inhibitors. If antifungal therapy is needed, hold finerenone for the course and check potassium before restarting.
What other medicines interact with Posaconazole?
MediHelp also lists interactions of Posaconazole with, for example, Artemether, Avanafil, Cobimetinib. The full list is on the Posaconazole page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
