藥物交互作用
Fludrocortisone + Mifepristone
嚴重程度: 禁忌併用
Fludrocortisone and Mifepristone: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Mifepristone is an antiglucocorticoid, and its labelling for abortion contraindicates long-term corticosteroid therapy because glucocorticoid replacement may be rendered ineffective. Adrenal crisis is a concern in patients taking fludrocortisone with glucocorticoid replacement.
用白話說明這項交互作用的意義
Fludrocortisone and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Fludrocortisone belongs to Endocrine; Mifepristone belongs to Endocrine.
為什麼會發生
Glucocorticoid receptor blockade reducing replacement efficacy
處置方式
Avoid; if mifepristone is essential, coordinate with an endocrinologist and increase glucocorticoid cover as needed.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Fludrocortisone 的其他交互作用
- Aldesleukin + Fludrocortisone 嚴重
- Amphotericin b + Fludrocortisone 嚴重
- Bcg vaccine live + Fludrocortisone 嚴重
- Fludrocortisone + Influenza virus vaccine quadrivalent intranasal 嚴重
- Fludrocortisone + Measles mumps and rubella vaccine live 嚴重
- Fludrocortisone + Measles mumps rubella and varicella vaccine live 嚴重
Mifepristone 的其他交互作用
常見問題
Can I take Fludrocortisone with Mifepristone?
MediHelp rates the interaction as contraindicated. Fludrocortisone and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mifepristone is an antiglucocorticoid, and its labelling for abortion contraindicates long-term corticosteroid therapy because glucocorticoid replacement may be rendered ineffective. Adrenal crisis is a concern in patients taking fludrocortisone with glucocorticoid replacement.
How serious is the interaction between Fludrocortisone and Mifepristone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid; if mifepristone is essential, coordinate with an endocrinologist and increase glucocorticoid cover as needed.
What other medicines interact with Fludrocortisone?
MediHelp also lists interactions of Fludrocortisone with, for example, Aldesleukin, Amphotericin b, Bcg vaccine live. The full list is on the Fludrocortisone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
