跳至主要內容
MediHelp
MediHelp 藥品參考

藥物交互作用

Glyceryl trinitrate pr + Vardenafil

嚴重程度: 禁忌併用

Glyceryl trinitrate pr and Vardenafil: contraindicated interaction.

最後更新

僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Vardenafil potentiates the vasodilating effect of nitrates, including rectal glyceryl trinitrate. The result can be severe, potentially fatal hypotension, syncope or myocardial ischemia.

用白話說明這項交互作用的意義

Glyceryl trinitrate pr and Vardenafil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

證據等級: High

為什麼會發生

PDE5 inhibition prevents cGMP breakdown, amplifying nitric-oxide-mediated vasodilation from the nitrate.

處置方式

Do not use together. Avoid nitrates for at least 24 hours after vardenafil, and seek urgent care if chest pain occurs after a dose.

可向藥師詢問的問題

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用，即可解鎖 Glyceryl trinitrate pr 與 Vardenafil 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription
建立免費帳號 登入

在網頁版免費試用 Pro+ 14 天，無需信用卡。

常見問題

Can I take Glyceryl trinitrate pr with Vardenafil?

MediHelp rates the interaction as contraindicated. Glyceryl trinitrate pr and Vardenafil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Vardenafil potentiates the vasodilating effect of nitrates, including rectal glyceryl trinitrate. The result can be severe, potentially fatal hypotension, syncope or myocardial ischemia.

How serious is the interaction between Glyceryl trinitrate pr and Vardenafil?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together. Avoid nitrates for at least 24 hours after vardenafil, and seek urgent care if chest pain occurs after a dose.

What other medicines interact with Vardenafil?

MediHelp also lists interactions of Vardenafil with, for example, Amyl nitrite, Isosorbide dinitrate, Isosorbide mononitrate. The full list is on the Vardenafil page.

在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查

在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。

下載於App Store 立即下載Google Play

依 A–Z 瀏覽 · 藥物交互作用

取得 App 登入