藥物交互作用
Ifosfamide + Sargramostim
嚴重程度: 中度
Ifosfamide and Sargramostim: moderate interaction.
最後更新
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摘要
Sargramostim stimulates proliferation of myeloid progenitor cells, which makes them more susceptible to damage from cytotoxic drugs. Giving it close to ifosfamide may worsen myelosuppression or blunt its intended benefit.
用白話說明這項交互作用的意義
Ifosfamide and Sargramostim can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ifosfamide belongs to Oncology; Sargramostim belongs to Miscellaneous.
為什麼會發生
Growth factor-driven cycling of hematopoietic progenitors increases their sensitivity to cytotoxic chemotherapy.
處置方式
Do not give sargramostim within 24 hours before or after ifosfamide. Monitor blood counts throughout treatment.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Ifosfamide 的其他交互作用
Sargramostim 的其他交互作用
常見問題
Can I take Ifosfamide with Sargramostim?
MediHelp rates the interaction as moderate. Ifosfamide and Sargramostim can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sargramostim stimulates proliferation of myeloid progenitor cells, which makes them more susceptible to damage from cytotoxic drugs. Giving it close to ifosfamide may worsen myelosuppression or blunt its intended benefit.
How serious is the interaction between Ifosfamide and Sargramostim?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give sargramostim within 24 hours before or after ifosfamide. Monitor blood counts throughout treatment.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
